Nitrofurantoin can stop the oral typhoid vaccine from working. This is because it can affect the results of some diagnostic tests. If you are due to have any medical or dental treatment, tell the person carrying out the treatment that you are taking nitrofurantoin. There is no need to use additional precautions for any bouts of sickness or diarrhoea which last for less than 24 hours. If this should happen, ask your doctor or pharmacist for advice about what additional contraceptive precautions to use over the following few days. If you are taking the contraceptive 'pill' at the same time as this antibiotic, the effectiveness of the 'pill' can be reduced if you have a bout of sickness (vomiting) or diarrhoea which lasts for more than 24 hours. Some antacids can interfere with nitrofurantoin and stop it from working properly. If you buy any medicines, check with a pharmacist that they are suitable for you to take with nitrofurantoin. Nitrofurantoin can turn your urine a yellow/brown colour. This is because some bacteria are resistant to some types of antibiotics. If your symptoms do not improve despite taking nitrofurantoin, go back to see your doctor, as you may need an alternative antibiotic. Most people improve within a few days of starting treatment. Try to take the correct number of doses each day but do not take two doses at the same time to make up for a missed dose. If you forget to take a dose at your usual time, take it as soon as you remember. If you have had several urine infections in a short period of time, your doctor will prescribe a longer course of treatment for you, often for six months. Most people taking nitrofurantoin are prescribed a short course of treatment which usually lasts between 3-7 days. It is important you do this even if you feel well, otherwise your infection may come back. Keep taking the tablets/capsules until the course is finished. Space them out evenly throughout the day - this means that tablets/capsules prescribed four times a day should ideally be taken every six hours, those prescribed twice a day should be taken every 12 hours, and those prescribed once a day should be taken every 24 hours. Take each of your doses with a snack or after eating a meal. The directions for taking your doses will be printed on the label of the pack of tablets/capsules to remind you about what the doctor said to you. Your dose will depend upon whether you are being treated because you have an infection, or to prevent an infection from coming back. 
Take nitrofurantoin tablets/capsules exactly as your doctor tells you to. NITROFURANTOIN MONO MAC 100MG CAPS WHAT IS IT USED FOR FULL
It will give you more information about nitrofurantoin, and will also provide you with a full list of the side-effects which you could experience from taking it.
Before you start the treatment, read the manufacturer's printed information leaflet from inside the pack. If you have ever had an allergic reaction to a medicine. This includes any medicines which are available to buy without a prescription, as well as herbal and complementary medicines. If you are taking any other medicines. If you have been told you have one of the following rare inherited conditions: porphyria or glucose-6-phosphate dehydrogenase (G6PD) deficiency. If you have a problem where your nerves cause pain or numbness, called peripheral neuropathy. If you have been told you have anaemia, or if you have low levels of vitamin B or folic acid. If you have diabetes (diabetes mellitus). If you have any problems with the way your liver works, or if you have any problems with the way your kidneys work. Although nitrofurantoin can be taken during pregnancy, it is still important that you tell your doctor about being pregnant. 
For these reasons, before you start taking nitrofurantoin it is important that your doctor knows: Some medicines are not suitable for people with certain conditions, and sometimes a medicine can only be used if extra care is taken.
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